Protein Design
Design, diversify, and score your proteins with the RFdiffusion pipeline. Create novel proteins or optimize existing ones with a streamlined process.
Watson et. al.
Design, diversify, and score your proteins with RFdiffusion pipeline
Protein structure to sequence prediction
Dauparas et. al
Design ligand-binding proteins with RFdiffusion All Atom
Krishna et. al.
Design macrocyclic proteins
Rettie et. al
Generate antibodies optimized for a given property
Gruver et. al
Design de novo binders for your target
Pacesa et. al
Atom-level enzyme active site scaffolding
Ahern et. al
Design sequences for antibodies
Hummer et. al
Design CDR sequence and structure for antibodies
Luo et. al
Design property-aware CDR sequence/structure
Villegas-Morcillo et. al
Language models to recommend mutations for increased antibody binding affinity
Hie et. al
Design or diversify proteins
Watson et. al
Motif scaffolding protein design
Yim et. al
Predict stability of point mutations
Dutton et. al
Inverse folding with modeling of small molecules and more
Invert Boltz-1 to design protein binders
Cho et. al
Conditionally generate artificial enzymes
Illanes-Vicioso et. al
Antibody structure prediction, design, and optimization
Kong et. al
Generate novel protein sequences
Nijkamp et. al
Generate mutations with directed evolution
Emami et. al
Design cyclic peptides
Mutate protein complexes with structure-informed language model
Varun R. Shanker et al. et. al
Genetic algorithm-based protein binder optimization pipeline
Goudy OJ et. al
Efficient binder design
Frank et. al
Solubilize membrane proteins
Protein design with Chai verification
Generate sequences given structure via reversing AlphaFold
Hybrid antibody design using AbLang + ProteinMPNN ensemble
del Alamo et. al
Optimize antibody/nanobody sequence affinity
Ruffolo et. al
Design thermostable proteins
Ertelt et. al
Antibody sequence design
Dreyer et. al
ML-assisted Directed Evolution
J. Funk et. al